National preparedness for a new strain of influenza or another novel infectious disease is an important national task. In order to sufficiently prepare, activities that must occur include: revision of national plans; operational planning and simulation exercises; integration of HPAI and pandemic preparedness activities into the control framework for a range of communicable diseases; addressing prevention of priority zoonotic disease that threatens human health, extending the focus of these from the health of poultry to other livestock and wildlife, and considering the health of the agro-ecosystems of animals and humans residence and interaction.